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The murine fibroblastic cell line L929 was used as a validation control for this procedure, and similar results were obtained (Supplementary Fig

Rayman, 2012)

Based on REDEFINE trial populations and the NDA submission terms, expected eligibility criteria are: BMI 30 , or BMI 27 with at least one weight-related condition such as hypertension, dyslipidemia, type 2 diabetes, or obstructive sleep apnea Adults 18 years or older Not pregnant or breastfeeding Contraindications will likely include: personal or family history of MTC or MEN 2 syndrome, prior serious allergic reaction to semaglutide or cagrilintide, and active pancreatitis

Arch Dermatol Res 317 , 591 (2025)

2021 Mar 6;14(1):49

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